专利摘要:
valve trocar cannula. the present invention relates to a trocar cannula (101) that can be configured for insertion into an eye, to facilitate the insertion and removal of instruments during surgery in various embodiments. the cannula can be attached to an overcap (103) to inhibit rotation of the overcap relative to the cannula), which includes a seal (111). in some embodiments, the seal may be overmoulded on the overcap, or it may include a insert, which is attached between the cannula and the overcap, to inhibit rotation relative to the cannula and overcap. in some embodiments, the cannula and overcap can be tightened together by a tongue / groove interface (107,109), permanently, so that the cannula and overcap cannot be separated without damaging the cannula or overcap. in some embodiments, a slit cannula may be receivable at the cut of the seal, to allow fluids to exit the eye through the cannula (which may include an indentation for frictionally coupling the slit).
公开号:BR112012017771B1
申请号:R112012017771-0
申请日:2010-11-22
公开日:2020-07-14
发明作者:Jose Lopez;Anil Patnala;Michael Martin
申请人:Alcon Research, Llc;
IPC主号:
专利说明:

PRIORITY CLAIM
[0001] This patent application claims the priority benefit of US provisional patent application serial number 61 / 289,449, entitled "OPHTHALMIC VALVED TROCAR CANNULA", filed on December 23, 2009, whose inventors are Jose Luis Lopez, Anil K. Patnala and Michael M. Martin, which is hereby incorporated by reference, in its entirety, as if presented entirely and completely in this specification. FIELD OF THE INVENTION
[0002] The present invention generally relates to ophthalmic surgery. More particularly, but not by way of limitation, the present invention relates to ophthalmic trocar cannulas or slits. DESCRIPTION OF RELATED TECHNIQUE
[0003] Microsurgical instruments can be used by surgeons to remove tissue from delicate and restricted spaces in the human body, for example, in eye surgery (such as procedures for removing the vitreous, sugar, scar tissue or crystalline lens). These instruments can include a control console and a surgical manual instrument, with which the surgeon dissects and removes tissue. With regard to posterior segment surgery, the manual instrument can be a vitreous cutter probe, a laser probe or an ultrasonic fragmentator for cutting or fragmenting tissue, and can be connected to the control console by an air pressure line ( pneumatic) and / or power cable, optical cable or flexible tubes, to supply an infusion fluid at the surgical site, and to remove or aspirate fluid and cut / fragmented tissue from the site. The cutting, infusion and suction functions of the hand instrument can be controlled by the re-moto control console, which not only provides power to the surgical hand tool (s) (for example, rotating or reciprocating cutting blade, or a ultrasonically vibrated needle), but they can also control the flow of infusion fluid and provide a vacuum source (relative to the atmosphere) for aspirating fluid and cut / fragmented tissue. The console functions can be controlled manually by the surgeon (for example, using a key or a foot operated control).
[0004] During posterior segment surgery, the surgeon can use various instruments or handpieces, during the procedure. This procedure may require that these instruments be inserted into and removed from the incision. Such repeated removal and insertion can cause trauma to the eye at the incision site. To address this concern, cannulas equipped with cubes were developed at least in the mid-1980s. These devices may include a narrow tube with a stuck hub. The tube can be inserted through an incision in the eye to the cube, which can act as a stop, preventing the tube from entering the eye completely. The cube can be sewn into the eye to prevent inadvertent removal. Surgical instruments can be inserted into the eye through the tube, and the tube can protect the side wall from the incision from repeated contact by the instruments. In addition, the surgeon can use the instrument, by manipulating the instrument when it is inserted into the eye through the tube, to help position the eye during surgery. The disadvantages of prior art cannulae may include the height of the projection on the surface of the eye, as well as the lack of any means to control the loss of intraocular pressure, during exchange or removal of the instrument. The eye, being a pressurized bulb, can expel aqueous or vitreous humor out of the open cannula when a surgical device is not present. With prior art cannulas, the loss of intraocular pressure was prevented by inserting a plug or cap into the tube to seal the cannula and prevent the expression of fluid and tissue. This can be a time-intensive process, which may require additional instrumentation, as well as the help of other operating room personnel, and may increase the risk of postoperative infection. SUMMARY OF THE INVENTION
[0005] In various embodiments, a trocar cannula can be configured for insertion into an eye, to facilitate the insertion and removal of instruments during surgery. The cannula can be attached to an overcap (attached to inhibit rotation of the overcap relative to the cannula). The overcap may include a seal to inhibit fluid flow out of the cannula (when an instrument is not inserted), while the cannula is inserted into the eye. In some embodiments, the seal can be molded on the overcap, or it can include a wafer, which is fixed between the cannula and the overcap, so that the seal does not rotate in relation to the cannula and the overcap. In some embodiments, the cannula and overcap can be received together via a tongue / groove interface permanently, so that the cannula and overcap can not be separated without damaging at least part of the cannula or overcap. In some embodiments, a slit cannula may be slidably receivable when cutting the seal to allow fluids to exit the eye through the cannula. In some embodiments, the cannula may include at least one indentation for frictionally coupling a part of the slot when the slot is inserted into the cannula. BRIEF DESCRIPTION OF THE DRAWINGS
[0006] For a more complete understanding of the present invention, reference is made to the description presented below, made in conjunction with the attached drawings, in which:
[0007] figure 1 shows a cannula and an overcap, according to an embodiment;
[0008] figure 2 illustrates the cannula affixed to the overcap, according to an embodiment;
[0009] figure 3a shows a view from the top showing the cut in the overcap seal, according to an embodiment;
[00010] figure 3b illustrates a side view of the cannula and overcap with several exemplary dimensions, according to an embodiment;
[00011] figures 4a - 4d illustrate cross sections of overcap and seal embodiments;
[00012] figure 5a illustrates the cannula in a changer insertion device, according to an embodiment;
[00013] figure 5b illustrates the cannula in a trocar insertion device with a transport cap, according to an embodiment;
[00014] figures 6a - b illustrate a slit, according to an embodiment;
[00015] figure 7 shows a slot in the valve trocar cannula, according to an embodiment;
[00016] figure 8 shows a cross section of the slot in the valve cannula according to an embodiment;
[00017] figures 9a - b illustrate a second embodiment of a crack;
[00018] figures 10a - c illustrate a third embodiment of a slit;
[00019] figure 11 illustrates a flow chart of a process for forming the valve cannula according to an embodiment;
[00020] figure 12 illustrates a flow chart of a process for forming the valve cannula according to another embodiment;
[00021] figure 13 illustrates a flow chart of a method for using the slit with the valve trocar cannula, according to an embodiment; and
[00022] figure 14 illustrates a valve trocar cannula inserted into an eye, according to an embodiment.
[00023] It should be understood that both the foregoing general description and the detailed description presented below are only exemplary and explanatory, and are intended to provide a further explanation of the present invention, as claimed. DETAILED DESCRIPTION OF THE ACCOMPLISHMENTS
[00024] Figure 1 illustrates an embodiment of a trocar cannula 101 and an overcap 103. The trocar cannula 101 can be configured for insertion into an eye, to facilitate the insertion and removal of instruments during surgery. The cannula 101 may include an axis 105, capable of extending to the eye (for example, a sclera, conjunctiva, etc.). In some embodiments, the cannula 101 can be attached to an overcap 103. For example, the cannula 101 can include one or more tabs 107, configured to engage the corresponding grooves 109 in the cannula 101 (for example, the cannula 101 shown in Figure 1 includes four tabs 107 to engage four corresponding slots 109 in overcap 103). Other fixations are also considered. For example, the cannula 101 may include the grooves and the overcap may include the tabs. In some embodiments, the cannula 101 can be attached to overcap 103 by adhesive, thermal bonding, etc. In some embodiments, a seal 111 can be coupled to overcap 103 (for example, seal 111 can be arranged at least partially between shaft 105 and overcap 109), to form an overmolded valve. As shown in figure 1, a surface of the seal 111 can be exposed in overcap 109. In some embodiments, the exposed surface of the seal 111 can include one or more cuts 113, to allow passage of surgical tools in the cannula 101. In the absence of a surgical instrument, seal 111 can inhibit fluid flow through seal 111.
[00025] Figure 2 illustrates an embodiment of the cannula 101 attached to overcap 103 (for example, after coupling the tongues 107 in the respective grooves 109). In some embodiments, the tongue / groove interface may prevent rotation of the overcap 103 relative to the cannula 101 (for example, during insertion of the cannula 101 into the eye). In some embodiments, the tabs 107 can be configured to permanently retain overcap 103 in cannula 101 (so that overcap 103 cannot be removed from cannula 101 without destroying part of cannula 101 and / or overcap 103). For example, tongues 107 (and cannula 101) can be made of stainless steel, and overcap 103 can be made of plastic (for example, polycarbonate). Other materials are also considered. Permanent retention between overcap 103 and cannula 101 can prevent inadvertent removal of overcap 103 from cannula 101 during surgery (e.g., vitreoretinal surgery).
[00026] Figure 3a illustrates a top view of an embodiment of cut 113 on seal 111 on overcap 103. Figure 3b illustrates a side view of an embodiment of cannula 101 and overcap 103 with various exemplary dimensions (provided in centimeters - inches). Other dimensions are also considered. For example, while the cannula 101 outer diameter is shown as 0.074 centimeter (0.029 inch) (corresponding to a 23 gauge cannula), in another embodiment, the cannula outer diameter can be 0.062 centimeter (0.0243 inch) (for a 25 gauge cannula). Other outside diameters are also considered.
[00027] Figures 4a - c illustrate the cross sections of an embodiment of the overcap 103 and the seal 111. The seal 111 can be made of an elastomer (for example, silicone). In some embodiments, seal 111 may be attached to overcap 103, to inhibit rotation of seal 111 relative to overcap 103. For example, seal 111 can be overmoulded into a depression 403 and one or more holes 401 in overcap 103 In some embodiments, seal 111 may include a silicon wafer 405, which is formed separately from overcap 103 and inserted between overcap 103 and cannula 101, during assembly of overcap 103 in cannula 101. In this case, seal 111 can be attached to overcap 103 and cannula 101 by a friction fit. Other fixings are also considered (for example, adhesive).
[00028] Figure 5a illustrates an embodiment of the cannula 101 in a trocar insertion device 501. In some embodiments, the trocar insertion device 501 may include a trocar blade 503, attached to a handle 505. In some embodiments, handle 505 can be made of plastic, and blade 503 can be made of stainless steel. Other materials are also considered. The trocar blade 503 may extend past the end of the shaft 105 and may include one or more sharp edges, to pierce an eye 1401 (e.g., drill a hole through the sclera 1403 and into the vitreous body 1405) for insertion of the cannula 101. In some embodiments, a guide 507 can fit into the guide groove 115, to inhibit the rotation of the overcap 103 / cannula 101 in relation to the cable 505, during insertion of the cannula 101 into the eye 1401. In some embodiments, the guide 507 can couple detach the guide groove 115, so that when the trocar insertion device 501 is removed from overcap 103 / cannula 101, guide 507 does not pull overcap 103 / cannula 101 out of eye 1401. For example, guide 507 it can frictionally guide the guide groove 115 with a frictional force, which is less than a frictional force exerted by the eye on the outer sides of the cannula 101, when the cannula 101 is in the eye.
[00029] Although guide 507 is illustrated as a tongue, to be received in guide groove 115, other locking items are also considered. For example, guide 507 and guide groove 115 can include different locking items (such as a ring and rod), or they can include other locking components (for example, locking magnets - one on each of the cable and overcap 103, coupling O-rings - one on each cable and overcap 103, etc.). In some embodiments, the interaction of guide 507 / guide groove 115 may prevent the route between the cannula 101 and overcap 103, so that any angular movement of the trocar cable 505, around the axis of the cable, can be transmitted to the overcap 103 and then to the cannula 101. This interaction can provide vitreoretinal surgeons with angular control of the cannula 101, in relation to the trocar shaft 505, during insertion of the cannula 101 into the sclera 1403. Figure 5b illustrates a cannula 101 in a trocar insertion device 501, with a transport cap 511 (which can be tightened on the cannula 101 and / or the trocar insertion device 501, to protect the cannula 101 and / or the trocar insertion device 501.
[00030] Figures 6a - b illustrate an embodiment of a 601 slit. Although the seal 111 of the valve trocar cannula protects the cannula from fluid flow to or from the cannula, when, for example, a surgical instrument is obstructing the cannula , a slit cannula 603 can be configured to slide in the cut 113 of the seal 111, to allow fluids to exit the eye through the cannula 101 (for example, see figure 7). In some embodiments, slot 601 can retain seal 111 in an open position, to allow fluid (for example, a gas or liquid) to escape through cannula 101. For example, a gas (or other fluid) can flow through the cannula. 101 and out of slot 601, during a procedure, to replace the gas with another fluid. Slit 601 may further include a rim 609 to provide a stop to prevent the slit from sliding across the seal 111. Slit cannula 603 may have an outside diameter that is less than an inner diameter of the trocar cannula 101, to allow the slit cannula 603 to slide past seal 111 and to the trocar cannula 101. Slit cannula 603 can further include a rim 609, at least one dimension large enough to prevent slit 601 slide fully into the trocar cannula 101 (for example, the diameter of the 609 rim may be larger than an inner diameter of the trocar cannula 101).
[00031] In some embodiments, the slot 601 may be a device separate from the cannula, to allow slot 601 to be inserted and removed, without adding or removing parts of the cannula 101 (for example, without having to remove the overcap 103 cannula 101). The size of the slit 601 may also allow a user (for example, a surgeon) to handle the slit 601 with fingers (or, for example, forceps), during the insertion and removal of the 601 slit.
[00032] In some embodiments, the slot 601 may include a flexible tube 605 (for example, a silicone tube), which frictionfully couples the slot cannula 603. Tube 605 can provide a visual indicator (for example, be at less partially transparent) of the expulsion process (for example, if a substance is overflowing from the eye (such as silicone during a viscous fluid control injection procedure), the silicone may flow into the 605 tube and be visible to a user. In some embodiments, the tube 605 can be used as a clamping surface for removing the cannula gap 101 (for example, to assist pinching with fingers or forceps). The cannula 603 can include a tube part 607, configured to receive flexible tube 605 along an outer perimeter of tube 607 (which can be made of, for example, stainless steel). In some embodiments, tube 607 and slit cannula 603 can be formed in one piece. figure 6b illustrates v several exemplary dimensions (provided in centimeters - inches), according to one embodiment. Other dimensions are also considered. In some embodiments, the dimensions of the slot 601 may allow instruments to pass through the slot 601, when the slot 601 is in the seal 111.
[00033] Figure 8 illustrates a cross section of an embodiment of the slot 601 in the cannula 101. In some embodiments, the cannula 101 can include at least one indentation 801, for frictionally coupling a part of the slot cannula 603, when the slot 601 is inserted into cannula 101. Indentation 801 can be sized to provide sufficient strength for slot 601, to hold slot 601 in place during a procedure. In some embodiments, the resistance between indentation 801 and slit 601 may be less than necessary to pull cannula 101 out of the eye when slit 601 cannula 101 is removed (so cannula 101 is not pulled out of the eye when slit 601 is pulled out of the cannula 101, while the cannula 101 is in the eye).
[00034] Other embodiments of the crack are also considered. For example, an embodiment of a slit 901 is shown in figures 9a - b. As seen in figures 9a - b, slot 901 may not include a tube 605, but may instead be a single piece. Slit 901 can be formed by deep drawing and can include a retaining item for joining with a retaining item in a cannula 101. Other forming techniques are also considered (for example, slit 901 can be shaped). In some embodiments, the slot may not include a retaining item. Yet another embodiment is shown as the slot 1001 in figures 10a - c. Slit 1001 can include a large bell-shaped entry, which can facilitate the insertion and removal of tools through slot 1001, when slot 1001 is inserted into a cannula 101. Slit 1001 can also include one or more items of retention 1003, to increase a tightness between the slot 1001 and the cannula 101, when the slot 1001 is inserted into a cannula 101.
[00035] Figure 11 illustrates a flow chart of a method for forming the valve trocar cannula, according to one embodiment. The elements provided in the flowchart are illustrative only. Several elements provided may be omitted, additional elements may be added, and / or several elements may be executed in an order different from that provided below.
[00036] In 1101, the overcap 103 can be formed. For example, overcap 103 can be molded to include through holes 401 to receive a silicone seal 111. Molding processes for overcap 103 can include injection molding, compression molding, blow molding, rotary molding, etc. Other techniques for forming overcap 103 are also considered (for example, casting).
[00037] In 1103, seal 111 can be overmoulded in overcap 103. For example, seal 111 can include an elastomer (such as silicone) molded into a depression 403 of overcap 103, and can flow into holes 401 to secure seal 111 in overcap 103. In some embodiments, overcap 103 can be placed in a mold, which defines spaces by overcap 103 for seal 111.0 elastomer can then be injected into the mold and flow through defined spaces, overcap 103 , to form the seal 111 on the overcap 103. Other manufacturing processes are also considered. For example, seal 111 and overcap 103 can be molded as one piece (for example, using the same material for both overcap 103 and seal 11 in a single mold). In some embodiments, seal 111 can be formed separately from overcap 103 (for example, see figure 10). In some embodiments, the seal can be formed with a cut 113, or the cut 113 can be formed on the seal 111, after the seal is formed (for example, the cut 113 can be made on the seal 111 using a sharp edge).
[00038] In 1105, a cannula 101 can be formed. For example, the cannula 101 can be formed by deep drawing. Deep cannula stamping 101 may include starting with a disc of material, which is compressed between one or more sets of male / female dies, for deep cannula stamping 101. A final step in forming the cannula may include removing excess material and / or cannula polishing 101. In some embodiments, the material between the tabs 107 can be sheared, between a male and a female matrix, or can be removed in other ways (e.g., cut). In some embodiments, the cannula 101 can be molded (for example, injection molding, compression molding, blow molding, rotary molding, extrusion molding, etc.). Other techniques for cannula formation are also considered. In some embodiments, the cannula 101 can be made of stainless steel or plastic. Other materials can also be used. In some embodiments, the cannula 101 can be formed with clamping tongues 107. For example, the dies or mold for the cannula 101 can include spaces for forming the tongues, or the tongues can be formed in the cannula 101 by working the machine. Other tongue-forming techniques are also considered.
[00039] In 1107, the overcap 103 can be attached to the cannula 101. For example, the tongues 107 can be tightened in the corresponding grooves 109. In some embodiments, overcap 103 may deform slightly to receive tabs 107, or tabs 107 may be configured to deform slightly, as overcap 103 is compressed in cannula 101, and then return to its initial condition, as the corresponding grooves 109 pass through the tabs 107. The tabs 107 can be sufficiently rigid (for example, made of stainless steel), so that the overcap 103 cannot be removed from the cannula 101 without destroying part of the cannula 101 and / or overcap 103.
[00040] Figure 12 illustrates a flow chart of a process for forming the valve cannula, according to another embodiment. The elements provided in the flowchart are illustrative only. Several elements provided may be omitted, additional elements may be added and / or several elements may be executed in an order different from that provided below.
[00041] In 1201, an overcap 1103 can be formed (for example, by molding). In some embodiments, overcap 1103 may be formed with receiving grooves 109.
[00042] In 1203, a seal 111 (such as a 405 silicone insert) can be formed. In some embodiments, the silicone pad 405 can be molded with a cut 113, or the cut 113 can be formed on the silicon pad 405, after molding (for example, the cut 113 can be made on the silicone pad using an edge acute).
[00043] In 1205, the cannula 101 can be formed. For example, the cannula 101 may be molded of stainless steel and may include tabs 107.
[00044] In 1207, the silicone insert 405 can be inserted between the cannula 101 and the overcap 103, and the overcap 103 can be attached to the cannula 101 (for example, the overcap 103 can be tightened on the cannula 101, so that grooves 109 can receive tabs 107).
[00045] Figure 13 illustrates a flow chart of a method for using the crack with the valve trocar cannula, according to one embodiment. The elements provided in the flowchart are illustrative only. Several elements provided may be omitted, additional elements may be added and / or several elements may be executed in an order different from that provided below.
[00046] In 1301, the trocar blade 503 can be inserted through slot 113 in seal 111 and cannula 101. In 1303, eye 1401 can be pierced with the trocar blade 503, and cannula 101 can be pushed into the eye . In 1305, the trocar blade 503 and the cannula 101 can be rotated, if necessary, during insertion. In 1307, the trocar blade 503 can be removed, leaving the cannula 101 in the eye 1401. In 1309, a slot 601 can be inserted, if necessary, to open the seal 111, to allow fluid / gas to exit through the cannula 101 and out of eye 1401. Slit 601 can be removed and / or reinserted, if necessary, into seal 111 and cannula 101, without removing cannula 101 from the eye, during the procedure. The insertion of the removal of the slot 601 can be done using, for example, the user's fingers or a pair of forceps.
[00047] Several modifications can be made to the embodiments presented by a person skilled in the art. Other embodiments of the present invention will become apparent to those skilled in the art of considering this specification and the practice of the invention described in this document. It is intended that the present specification and the examples are considered only as examples, with a true scope, and the spirit of the invention being indicated by the claims and their equivalents presented below.
权利要求:
Claims (11)
[0001]
1. Apparatus, comprising: a cannula (101) configured for insertion into an eye; an overcap (103) attached to the cannula (101), where the overcap (103) is configured to be devoid of rotation relative to the cannula (101); and a seal (111) between the cannula and the overcap, where the seal (111) is configured to allow surgical tools to pass into the cannula by means of a cut (113) in the seal, while inhibiting the flow of fluid through the seal when a surgical tool is missing from the seal; characterized by the fact that: the seal (111) is made of an overmolded elastomer in a depression (403) in the overcap (103); and wherein the seal is molded into a hole (401) in the overcap (103).
[0002]
2. Apparatus according to claim 1, characterized by the fact that the elastomeric seal (111) comprises silicone overmolded in a depression (403) in the overcap (103).
[0003]
Apparatus according to claim 2, characterized in that the elastomeric seal (111) is molded in a plurality of holes (401) in the overcap (103).
[0004]
Apparatus according to claim 1, characterized by the fact that: the cannula (101) includes at least one tongue (107); the overcap (103) includes at least one groove (109); and the overcap (103) is attached to the cannula (101) by receiving at least one tongue (107) in at least one groove (109).
[0005]
Apparatus according to claim 1, characterized in that it further comprises a slit cannula (603) configured to slide into the cut (113) of the seal (111), to allow fluids to escape through the cannula (101) .
[0006]
Apparatus according to claim 5, characterized in that the cannula (101) comprises at least one indentation for frictionfully coupling a part of the slot (601), when the slot is inserted into the cannula.
[0007]
Apparatus according to claim 1, characterized in that the overcap comprises a guide groove (115), in which the guide groove is configured to receive a guide from a trocar cable (505), and in which the interaction between the guide groove (115) and the guide inhibit the rotation of the overcap relative to the cable during insertion of the cannula.
[0008]
8. Apparatus according to claim 7, characterized by the fact that it is combined with: a cable (505); a trocar blade (503) coupled to the handle (505); and the overcap (103) includes a cut (113) configured to receive the trocar blade (503) through it, in which the elastomeric seal (111) between the cannula and the overcap (103) is configured to allow the passage of tools surgical to the cannula by cutting the seal, inhibiting fluid flow through the seal when a surgical tool is missing from the seal; and where the cable further comprises a guide (501), and where the guide groove (115) is configured to receive the guide from the cable, and where the interaction between the guide groove and the guide inhibits rotation of the cable overcap during insertion of the cannula into an eye.
[0009]
9. Method for forming an apparatus as defined in king-vindication 1 characterized by the fact that it comprises the steps of: forming (1101) an overcap (103); forming (1105) a cannula (101); fix (1103) an elastomeric seal (111) to the overcap (103) by overmolding the seal in a depression in the overcap, where the seal is configured to allow surgical tools to pass through the cannula through a cut (113) in the seal while inhibiting the flow of fluid through the seal when a surgical tool is missing from the seal; and fixing (1107) the overcap in the cannula, where the overcap is configured to be devoid of rotation in relation to the cannula (101).
[0010]
Method according to claim 9, characterized in that fixing (1103) the elastomeric seal (111) on the overcap comprises molding silicone in a depression (403) of the overcap (103).
[0011]
Method according to claim 9, characterized in that: forming (1101) the overcap (103) comprises forming at least one groove (109) in the overcap (103); forming the cannula (101) comprises forming at least one tongue (107) in the cannula; and wherein attaching the overcap to the cannula comprises receiving at least one tongue in at least one groove.
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法律状态:
2019-01-08| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
2019-07-23| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
2019-12-24| B06A| Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]|
2020-03-17| B25A| Requested transfer of rights approved|Owner name: ALCON RESEARCH, LLC (US) |
2020-05-05| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
2020-07-14| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/11/2010, OBSERVADAS AS CONDICOES LEGAIS. |
优先权:
申请号 | 申请日 | 专利标题
US28944909P| true| 2009-12-23|2009-12-23|
US61/289,449|2009-12-23|
PCT/US2010/057582|WO2011087577A1|2009-12-23|2010-11-22|Ophthalmic valved trocar cannula|
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